Casting (30)
Jon Cryer
Alan Harper
Conchata Ferrell
Berta
Angus T. Jones
Jake Harper
Marin Hinkle
Judith Harper
Holland Taylor
Evelyn Harper
Charlie Sheen
Charlie Harper
Ashton Kutcher
Walden Schmidt
Melanie Lynskey
Rose
Courtney Thorne-Smith
Lyndsey Mackelroy
Ryan Stiles
Herb
Amber Tamblyn
Jenny
Jennifer Bini Taylor
Chelsea
Sophie Winkleman
Zoey
April Bowlby
Kandi
Graham Patrick Martin
Eldridge Mackelroy
Jane Lynch
Dr. Linda Freeman
Judy Greer
Bridget Schmidt
Robert Clotworthy
TV Announcer (voice)
Kelly Stables
Melissa
D. B. Sweeney
Larry
Maggie Lawson
Ms. McMartin
J.D. Walsh
Gordon
Brooke D'Orsay
Kate
Rebecca McFarland
Leanne
Jenny McCarthy
Courtney
Clark Duke
Barry
James Edson
Stephan 'Bobby' Wasserstein
Mimi Rogers
Robin Schmidt
Kimberly Williams-Paisley
Gretchen