Reparto (30)
Bob Hoskins
Eddie Valiant
Christopher Lloyd
Judge Doom
Joanna Cassidy
Dolores
Charles Fleischer
Roger Rabbit / Benny The Cab / Greasy / Psycho (voice)
Kathleen Turner
Jessica Rabbit (voice) (uncredited)
Stubby Kaye
Marvin Acme
Alan Tilvern
R.K. Maroon
Richard LeParmentier
Lt. Santino
Lou Hirsch
Baby Herman (voice)
Betsy Brantley
Jessica's Performance Model
Joel Silver
Raoul
Paul Springer
Augie
Richard Ridings
Angelo
Edwin Craig
Arthritic Cowboy
Lindsay Holiday
Soldier
Mike Edmonds
Stretch
Morgan Deare
Editor / Gorilla (voice)
Danny Capri
Kid #1
Christopher Hollosy
Kid #2
Jean-Paul Sipla
Kid #3
Laura Frances
Blonde Starlet
Joel Cutrara
Forensic #1
Billy J. Mitchell
Forensic #2
Eric B. Sindon
Mailman
Ed Herlihy
Newscaster
James O'Connell
Conductor
Eugene Gutierrez
Teddy Valiant
April Winchell
Mrs. Herman (voice)
Mae Questel
Betty Boop (voice)
Mel Blanc
Daffy Duck / Tweety / Bugs Bunny / Sylvester / Porky Pig (voice)