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Keketso Semoko
Cast · Known for Isidingo
Keketso Semoko is a South African actress best known for her role as Ma Agnes Matabane in the SABC3 soapie Isidingo, from July 1998 to August 2014.

Renate Stuurman
Renate Stuurman is a South African actress best known for her soapie roles as Denise in SABC2's 7de Laan, as Jade in SABC3's Isidingo and as Tamia Bardill in Scandal!, on e.tv. Born and raised in Cape Town, Renate pursued studies in drama at Rhodes University, Grahamstown with renowned actor/playwright, Andrew Buckland and top choreographer Gary Gordon. Having gained a degree in drama, she moved to Johannesburg in 1999. It was not long before she won cameo roles in the e.tv series Schoop Schoombie, SOS and Backstage. Lead roles include the role of Denise in the Afrikaans soap 7de Laan; the role of Kim in the Franz Marx drama series The Res; the role of Jade in the daily English soap Isidingo; and the role of Tamia Bardill in e.tv's newsroom drama Scandal!. She also played a journalist in the SABC2 drama series Song vir Katryn. Other television series she has appeared in include Jozi Streets, Jozi-H and Riemvasmaak. In 2009 she played the role of 21-16 in the British-American television mini-series The Prisoner, a remake of the classic 1960s series of the same name. In 2010 she starred as Roxanne Davids in the SABC2 drama series The Mating Game, from March to June.

Elma Postma
Elma Postma (born 6 September 1978) is a South African actress and presenter. She is best known for her acting roles on 7de Laan, Binnelanders and Isidingo.

Gérard Rudolf
Gérard Rudolf is a South African actor. He has starred in many TV series and films since 1992, including the 2013 Bengali film Chander Pahar and the SABC 3 soap Isidingo. He stars as Boef Beukes in the 2023 M-Net series Devil's Peak, based on the novel of the same name by Deon Meyer.

Michelle Botes
Cast · Known for Isidingo
Michélle Botes was a South African actress, language instructor, designer and aromatherapist. She is best known for her roles in the television soaps Legacy (2020), Isidingo (1998) and Arende (1994)

Bianca Amato
Cast · Known for Isidingo
Bianca Amato is a South African actress known for her work in American theatre, as a prolific audiobook performer and for her portrayal of Philippa De Villiers in the original cast of the South African soap opera Isidingo. Amato was a member of the original cast of the long running South African soap opera Isidingo, portraying Philippa De Villiers from 1998 to 2001. The character's relationship with mine manager Derek Nyathi (Hlomla Dandala) featured the first interracial kiss, and was the first interracial romance, to be depicted on South African television. The storyline has been described as "groundbreaking and big news in post apartheid South African television". Of the experience Amato said, "It was wonderful to be part of the slow but healthy process that shifted people's attitudes." Her performance in Isidingo earned Amato an Avante for Best Actress in a Television Series. In 2002, Amato was granted a United States Permanent Resident Card as an "Alien of Extraordinary Ability" in the arts and emigrated to the United States. After appearing in a 2002 episode of the HBO series Sex and the City, she played several leading roles with the Guthrie Theater in Minneapolis, Minnesota between 2003 and 2005. Since 2009 Amato has guest starred in several U.S. TV series. In 2015, Amato portrayed Delia Alexander in the 2015 PlayStation Network series Powers. Amato appeared in the original Broadway production of Tom Stoppard's Tony Award-winning trio of plays The Coast of Utopia (2006–07), as well as the 2013–14 Broadway revival of Shakespeare's Macbeth. She also understudied the roles of Hannah Jarvis and Lady Croom in the 2011 Broadway revival of Stoppard's Arcadia. Off-Broadway, Amato has appeared in Bill Irwin's Mr. Fox: A Rumination (2004), and as Emma in Trumpery (2007). She later costarred as Calantha in The Broken Heart in 2012, and played the leading role of Olga Knipper in Neva in 2013. Amato also starred as Amanda in a production of Noël Coward's Private Lives directed by Maria Aitken, first presented in 2012 at the Huntington Theatre Company in Boston, and again in 2014 at the Shakespeare Theatre Company's Lansburgh Theatre in Washington, D. C. In 2014 she also portrayed Regan in the Theatre for a New Audience production of King Lear in New York. Amato has narrated over 40 audiobooks, including most of the historical novels in the Cousins' War series written by Philippa Gregory, and Charles Stross' 2008 science fiction novel Saturn's Children. She also voiced the 2006 gothic novel The Thirteenth Tale by Diane Setterfield, which had risen to No. 1 on The New York Times Best Seller list in its second week of publication.

Trevor Noah
Cast · Known for The Daily Show
Trevor Noah is a South African actor, presenter, comedian and radio DJ who began his career with a cameo role on the SABC3 soapie Isidingo, in 2002. After his stint on the show he spent two years years hosting an educational show for SABC2 during which time he started hosting his own radio show on Yfm called Noah's Ark. At Yfm his show was called Trevor Noah and was on between 00h00 and 03h00. He is also very involved in the South African comedy circuit and has performed at various comedy festivals. On television he hosted the SABC1 celebrity gossip show The Real Goboza in 2007 and also hosted SABC's sports show Siyadlala. In 2008 he was the runner-up on SABC2's reality dance competition Strictly Come Dancing 4, losing to actor Emmanuel Castis in the grand finale. His professional dance partner was Hayley Hammond. From May to August 2008 he was the co-host (with Pabi Moloi) of the SABC1 interactive dating game show The Amazing Date. He hosted the 3rd annual SAFTA Awards at the State Theatre in Pretoria on Saturday 7 February, 2009. Trevor was the host (along with Eugene Khoza) of the e.tv reality competition series The AXE Sweet Life from March to May, 2009. He hosted the 15th annual South African Music Awards (SAMAs) at the Sun City Superbowl on 2 May, 2009. He was invited back to host the SAMAs in 2010. Trevor began hosting his own talk show on M-Net in August 2010, entitled Tonight with Trevor Noah, based on international shows such as The Tonight Show with Jay Leno, The Late Show with Conan O'Brien and satirical fare like The Daily Show with Jon Stewart. The show moved to DStv's Mzansi Magic channel for it second season, which premiered on 5 November, 2010

Kim Suzanne Engelbrecht
Kim Suzanne Engelbrecht (born 20 June 1980 in Cape Town, South Africa) is a South African actress best known for her roles as Lolly de Klerk in the soap opera Isidingo, Sgt. Noma Banks on the Syfy TV show Dominion and Marlize DeVoe on The CW show The Flash.

Nathalie Boltt
Cast · Known for Riverdale
Nathalie Boltt (born 19 July 1973) is a South African actress known for Riverdale and District 9. Her initial break into acting was in her birth country, South Africa, as Joey Ortlepp on the SABC 3 drama Isidingo from 2001 to 2004. Internationally, she portrayed Penelope Blossom on The CW's teen drama series Riverdale from 2017 to 2023. She has been seen in the films District 9, Demonic, and the 2005 television remake of The Poseidon Adventure. She also voices the character of DottyWot in the New Zealand children's series The WotWots. Description above from the Wikipedia article Nathalie Boltt, licensed under CC-BY-SA, full list of contributors on Wikipedia.

Jamie Bartlett
Cast · Known for Isidingo
James Bartlett was a British-born South African actor. After completing high school he trained in speech and drama at the University of Cape Town followed by post Graduate Masterclasses at Chrysalis Theater Acting School. Bartlett was best known for roles in the TV series Isidingo and Rhythm City, but also played various film and stage roles. He died suddenly of a heart attack in South Africa in 2022.

Brandon Auret
Cast · Known for Chappie, They Will Kill You
Brandon Auret (born 27 December 1972) is a South African actor known for his role as Leon du Plessis in the SABC3 soap opera Isidingo. Description above from the Wikipedia article Brandon Auret, licensed under CC-BY-SA, full list of contributors on Wikipedia

Tertius Meintjes
Performed in the Afrikaans production of Equus (as “Alan Strang”), late 1970s. Other stage productions include Sing jy van Bomme (PACT 1988), Paulus (KKNK 2007). He wrote the stage play Dis Seker die Honde and the television screenplay The Pink Leather Chair. On television he played one of the lead roles in Plek van die Vleisvreters, had a lead role in Isidingo and played in numerous other productions.

David S. Lee
Cast · Known for Black Panther
David was born in 1971. David's career started in theater in South Africa in 1990. His most recent stage credits include :"I love you, You're perfect, Now change"; "The Official Tribute to the Blues Brothers"; "The Return to the Forbidden Planet" and "The Rocky Horror Show". He has an extensive list of commercial credits, a few of which have garnered awards world-wide. "Final Solution" is his first major film credit. His performance in the film has stirred up enough interest in The United States to land him a top U.S. Agent. He has just completed a co-starring role in the hit television series "Fastlane" on the Fox network for Warner Bros. and guest appearance in the series “Charmed”. He recently returned home to star in the “Isidingo” mini series “THE TRUTH” and will be shooting in Maputo on Ed Zwick’s film “Blood Diamond”.